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Within the pathogenesis of rheumatoid arthritis (RA), rheumatoid arthritis fibroblast-like synoviocytes (RA-FLS) have tumor-like traits, primarily manifested by hyperproliferation and resistance to apoptosis after which it should erode the bone and cartilage, ultimately resulting in joint destruction. Paris saponin VII (PS VII) is an lively compound derived from a conventional natural medication named Trillium tschonoskii Maxim, which …